Small Animal Clinical Nutrition

The most comprehensive and practical small animal nutrition resource available.

Chapter 57: Inflammatory Bowel Disease References


Allenspach K, Rüfenacht S, Sauter S, et al. Pharmacokinetics and clinical efficacy of cyclosporine treatment of dogs with steroid-refractory inflammatory bowel disease. Journal of Veterinary Internal Medicine 2006; 20: 239-244.

Baez JL, Hendrick MJ, Walker LM, et al. Radiographic, ultrasonographic, and endoscopic findings in cats with inflammatory bowel disease of the stomach and small intestine: 33 cases (1990-1997). Journal of the American Veterinary Medical Association 1999; 215: 349-354.

Belluzzi A, Boschi S, Brignola C, et al. Polyunsaturated fatty acids and inflammatory bowel disease. American Journal of Clinical Nutrition 2000; 72 (Suppl.): 339S-342S.

Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn’s disease. New England Journal of Medicine 1996; 334: 1557-1560.

Breitschwerdt EB, Ochoa R, Barta M, et al. Clinical and epidemiological characterization of a diarrheal syndrome in basenji dogs. Journal of the American Veterinary Medical Association 1982; 180: 914-920.

Breitschwerdt EB. Immmunoproliferative enteropathy of basenjis. Seminars in Veterinary Medicine and Surgery: Small Animal 1992; 7: 153-161.

Breuer RI, Buto SK, Christ ML, et al. Rectal irrigation with short-chain fatty acids for distal ulcerative colitis. Preliminary report. Digestive Diseases and Sciences 1991; 36: 185-187.

Craven M, Simpson JW, Ridyard AE, et al. Canine inflammatory bowel disease: Retrospective analysis of diagnosis and outcome in 80 cases (1995-2002). Journal of Small Animal Practice 2004; 45: 336-342.

Davenport DJ, Leib MS, Roth L. Progression of lymphocytic plasmacytic enteritis to lymphosarcoma in three cats. In: Proceedings. Seventh Annual Conference, Veterinary Cancer Society, Madison, WI, 1987: (Suppl.).

Davenport DJ. Gastrointestinal lymphosarcoma. In: August JR, ed. Consultations in Feline Internal Medicine 1. Philadelphia, PA: WB Saunders Co, 1991; 419-423.

Elwood CM, Rutgers HC, Batt RM. Gastroscopic food sensitivity testing in 17 dogs. Journal of Small Animal Practice 1994; 35: 199-203.

Evans SE, Bonczynski JJ, Broussard JD, et al. Comparison of endoscopic and full-thickness biopsy specimens for diagnosis of inflammatory bowel disease and alimentary tract lymphoma in cats. Journal of the American Veterinary Medical Association 2006; 229: 1447-1450.

Fiocchi C. Inflammatory bowel disease: Etiology and pathogenesis. Gastroenterology 1998; 115: 182-205.

Flesja K, Yri T. Protein-losing enteropathy in the Lundenhund. Journal of Small Animal Practice 1977; 18: 11-23.

Garcia-Sancho M, Rodriguez-Franco F, Sainz A, et al. Evaluation of clinical, macroscopic, and histopathologic response to treatment in nonhypoproteinemic dogs with lymphocytic-plasmacytic enteritis. Journal of Veterinary Internal Medicine 2007; 21: 11-17.

German AJ, Hall EJ, Day MJ. Chronic intestinal inflammation and intestinal disease. Journal of Veterinary Internal Medicine 2003; 17: 8-20.

German AJ, Hall EJ, Day MJ. Immune cell populations within the duodenal mucosa of dogs with enteropathies. Journal of Veterinary Internal Medicine 2001; 15: 14-25.

Griffiths AM, Ohlsson A, Sherman PM, et al. Meta-analysis of enteral nutrition as a primary treatment of active Crohn’s disease. Gastroenterology 1995; 108: 1056-1067.

Guilford WG, Jones BR, Markwell PJ, et al. Food sensitivity in cats with chronic idiopathic intestinal problems. Journal of Veterinary Internal Medicine 2001; 15: 7-13.

Guilford WG, Strombeck DR, Rogers Q, et al. Development of gastroscopic food sensitivity testing in dogs. Journal of Veterinary Internal Medicine 1994; 8: 414-422.

Guilford WG. Idiopathic inflammatory bowel diseases. In: Guilford WG, Center SA, Strombeck DR, et al, eds. Strombeck’s Small Animal Gastroenterology, 3rd ed. Philadelphia, PA: WB Saunders Co, 1996; 451-486.

Guilford WG. Nutritional management of gastrointestinal diseases. In: Guilford WG, Center SA, Strombeck DR, et al, eds. Strombeck’s Small Animal Gastroenterology, 3rd ed. Philadelphia, PA: WB Saunders Co, 1996a; 889-910.

Gunawardana S, Jergens AE, Ahrens FA, et al. Colonic nitrite and immunoglobulin G concentrations in dogs with inflammatory bowel disease. Journal of the American Veterinary Medical Association 1997; 211: 318-321.

Hall EJ, German AJ. Diseases of the small intestine. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine: Diseases of the Dog and the Cat, 6th ed. St. Louis, MO: Elsevier Saunders, 2005; 1332-1378.

Hall EJ. Inflammatory bowel disease. North American Veterinary Conference Clinician’s Brief. 2005; November 9-10.

Hanauer SB. Inflammatory bowel disease. New England Journal of Medicine 1996; 334: 841-848.

Hannah SS, LaFlamme DP, Marks SL. Hydrolyzed proteins in diets for the management of food hypersensitivity or inflammatory bowel disease. In: Proceedings. World Small Animal Veterinary Association/Federation European Companion Animal Veterinary Association World Congress, 2000: 517.

Harig JM, Soergel KH, Komorowski RA, et al. Treatment of diversion colitis with short-chain-fatty acid irrigation. New England Journal of Medicine 1989; 320: 23-28.

Hayden DW, van Kruiningen HJ. Eosinophilic gastroenteritis in German shepherd dogs and its relationship to visceral larva migrans. Journal of the American Veterinary Medical Association 1973; 162: 379-384.

Hendricks KM, Walker A. Zinc deficiency in inflammatory bowel disease. Nutrition Reviews 1988; 46: 401-408.

Henschkel RB, Menache CC, Megarian JT, et al. Enteral nutrition and corticosteroids in the treatment of acute Crohn’s disease in children. Journal of Pediatric Gastroenterology and Nutrition 2000; 31: 8-15.

Husain A, Korzenik JR. Nutritional issues and therapy in inflammatory bowel disease. Seminars in Gastrointestinal Disease 1998; 9: 21-30.

Inness VL, McCartney AL, Khoo C, et al. Molecular characterization of the gut microflora of healthy and inflammatory bowel disease cats using fluorescence in situ hybridization with special reference to Desulfovibrio spp. Journal of Animal Physiology and Animal Nutrition 2007; 91: 48-53.

Jamikorn UA, Harmon DL, Davenport DJ, et al. Fermentability of selected fibers by dog and cat fecal microflora (abstract). Annual Meeting. American Society of Animal Science, Indianapolis, IN, July 1999.

Jeejeebhoy KN. Nutritional aspects of inflammatory bowel disease. In: Kirsner JB, Shorter RG, eds. Inflammatory Bowel Disease, 4th ed. Baltimore, MD: Williams & Wilkins, 1995; 734-749.

Jergens AE, Gamet Y, Moore FM, et al. Colonic lymphocyte and plasma cell populations in dogs with lymphocytic-plasmacytic colitis. American Journal of Veterinary Research 1999; 60: 515-520.

Jergens AE, Moore FM, Haynes JS, et al. Idiopathic inflammatory bowel disease in dogs and cats: 84 cases (1987-1990). Journal of the American Veterinary Medical Association 1992; 201: 1603-1608.

Jergens AE, Moore FM, Kaiser MS, et al. Morphometric evaluation of immunoglobulin A-containing and immunoglobulin G-containing cells and T cells in duodenal mucosa from healthy dogs and from dogs with inflammatory bowel disease or nonspecific gastritis. American Journal of Veterinary Research 1996; 57: 697-704.

Jergens AE, Schreiner CA, Frank DE, et al. A scoring index for disease activity in canine inflammatory bowel disease. Journal of Veterinary Internal Medicine 2003; 17: 291-297.

Jergens AE. Feline idiopathic inflammatory bowel disease. Compendium on Continuing Education for the Practicing Veterinarian 1992; 14: 509-518.

Jergens AE. Inflammatory bowel disease: Current perspectives. Veterinary Clinics of North America: Small Animal Practice 1999; 29: 501-521.

Laflamme DP, Long GM. Evaluation of two diets in the nutritional management of cats with naturally occurring chronic diarrhea. Veterinary Therapeutics 2004; 5: 44-51.

Laflamme DP, Xu H, Long G. Dietary fat in the management of cats with naturally occurring chronic diarrhea. Compendium on Continuing Education for the Practicing Veterinarian 2007; 29 (Suppl.): 87.

Lee JY, Plakidas A, Lee WH, et al. Differential modulation of Toll-like receptors by fatty acids: Preferential inhibition of n-3 polyunsaturated fatty acids. Journal of Lipid Research 2003; 44: 479-486.

Leib MS, Sponenberg DP, Wilcke JR, et al. Suppurative colitis in a cat. Journal of the American Veterinary Medical Association 1986; 188: 739-741.

Leib MS. Diseases of the intestines. In: Leib MS, Monroe WE, eds. Practical Small Animal Internal Medicine. Philadelphia, PA: WB Saunders Co, 1997; 685-760.

Lewis JD, Fisher RL. Nutrition support in inflammatory bowel disease. Medical Clinics of North America 1994; 78: 1443-1456.

Lewis LD, Boulay JP, Chow FHC. Fat excretion and assimilation by the cat. Feline Practice 1979; 9: 46-49.

Ling SC, Griffiths AM. Nutrition in inflammatory bowel disease. Current Opinion in Clinical Nutrition and Metabolic Care 2000; 3: 339-344.

Littman MP, Giger U. Familial protein-losing enteropathy (PLE) and/or protein-losing nephropathy (PLN) in soft-coated wheaten terriers (SCWT) (abstract). Journal of Veterinary Internal Medicine 1990; 4: 133.

Lorenz R, Weber PC, Szimnau P, et al. Supplementation with n-3 fatty acids from fish oil in chronic inflammatory bowel diseaseA randomized, placebo-controlled, double blinded cross-over trial. Journal of Internal Medicine 1989; 225 (Suppl. 731): 225-232.

Lorenz-Meyer H, Bauer P, Nocolay C, et al. Omega-3 fatty acids and low carbohydrate diet for maintenance of remission in Crohn’s disease. A randomized controlled multicenter trial. Scandinavian Journal of Gastroenterology 1996; 31: 778-785.

Marks SL, LaFlamme DP. Dietary trial in dogs with inflammatory bowel disease utilizing a hydrolyzed protein diet. In: Proceedings. Purina Nutrition Forum, St. Louis, MO, 1998: 7.

Martin L, Matteson V, Wingfield W. Abnormalities of serum magnesium in critically ill dogs: Incidence and implications. Journal of Veterinary Emergency and Critical Care 1994 ;4: 15-20.

Mate J, Castanos R, Garcie-Samaniego J, et al. Does dietary fish oil maintain the remission of Crohn’s disease (CD): A study case control (abstract). Gastroenterology 1991; 100: A228.

Moore RP. Feline eosinophilic enteritis. In: Kirk RW, ed. Current Veterinary Therapy VIII. Philadelphia, PA: WB Saunders Co, 1983; 791-793.

Nelson RW, Dimperio ME, Long GG. Lymphocytic-plasmacytic colitis in the cat. Journal of the American Veterinary Medical Association 1984; 184: 1133-1135.

Nelson RW, Stookey LJ. Nutritional management of idiopathic chronic colitis in the dog. Journal of Veterinary Internal Medicine 1988; 2: 133-137.

Nguyen Van N, Taglinger K, Helps CR, et al. Measurement of cytokine mRNA expression in intestinal biopsies of cats with inflammatory enteropathy using quantitative real-time RT-PCR. Veterinary Immunology and Immunopathology 2006; 113: 404-414.

Roth L, Leib MS, Davenport DJ, et al. Comparisons between endoscopic and histologic evaluation of the gastrointestinal tract in dogs and cats: 75 cases (1984-1987). Journal of the American Veterinary Medical Association 1990; 196: 635-638.

Ruaux CG, Steiner JM, Williams DA. Early biochemical and clinical response to cobalamin supplementation in cats with signs of gastrointestinal disease and severe hypocobalaminemia. Journal of Veterinary Internal Medicine 2005; 19: 155-160.

Ruaux CG, Steiner JM, Williams DA. Metabolism of amino acids in cats with severe cobalamin deficiency. American Journal of Veterinary Research 2001; 61: 1852-1858.

Rutgers HC. SIBOGMore common than you think. In: Proceedings. Fourteenth Annual Veterinary Medical Forum, American College of Veterinary Internal Medicine, San Antonio, TX, 1996: 348-349.

Schreiner N, Allenspach K, Sauter S, et al. No changes in histological scoring, total number of infiltrating cells and number of T cells after treatment in dogs with chronic enteropathies. In: Proceedings. European College of Veterinary Internal Medicine–Companion Animals Congress 15th Annual Meeting. Glasgow, Scotland, September 2005: 207.

Simpson KW, Fyfe J, Cornetta A, et al. Subnormal concentrations of serum cobalamin (Vitamin B12) in cats with gastrointestinal disease. Journal of Veterinary Internal Medicine 2001; 15: 26-32.

Simpson KW. Feline inflammatory bowel disease: Moving beyond qualitative histology. In: Proceedings. Néstle Purina Nutrition Forum, September 25-28, 2003: 73-80.

Steiner JM. Feline triaditis. North American Veterinary Conference Clinician’s Brief March 2007: 7-10.

Stenson WF, Cort DC, Rodgers J, et al. Dietary supplementation with fish oil in ulcerative colitis. Annals of Internal Medicine 1992; 116: 609-614.

Sturniolo GC, Di Leo V, Ferronato A, et al. Zinc supplementation tightens “leaky gut” in Crohn’s disease. Inflammatory Bowel Disease 2001; 7: 94-98.

Suchodolski JS, Steiner JM. Laboratory assessment of gastrointestinal function. Clinical Techniques in Small Animal Practice 2003; 18: 203-210.

Sunvold GD, Fahey GC Jr, Merchen NR, et al. Dietary fiber for cats: In vitro fermentation of selected fiber sources by cat fecal inoculum and in vivo utilization of diets containing selected fiber sources and their blends. Journal of Animal Science 1995; 73: 2329-2339.

Sunvold GD, Fahey GC Jr, Merchen NR, et al. Dietary fiber for dogs: IV. In vitro fermentation of selected fiber sources by dog fecal inoculum and in vivo digestion and metabolism of fiber-supplemented diets. Journal of Animal Science 1995a; 73: 1099-1109.

Sunvold GD, Fahey GC Jr, Merchen NR, et al. In vitro fermentation of selected fibrous substrates by dog and cat fecal inoculum: Influence of diet composition on substrate organic matter disappearance and short-chain fatty acid production. Journal of Animal Science 1995b; 73: 1110-1122.

Tebeau C. Inflammatory bowel disease with a coronavirus twist. Veterinary Forum 2007; 56-62.

Toll J, Erb H, Birnbaum N, et al. Prevalence and incidence of serum magnesium abnormalities in hospitalized cats. Journal of Veterinary Internal Medicine 2002; 16: 217-221.

Vaden SL, Davenport DJ, Hammerberg B, et al. Gastroscopic food sensitivity testing and oral challenge in soft-coated wheaten terriers with protein-losing enteropathy and/or nephropathy (abstract). In: Proceedings. Sixteenth Annual Veterinary Medical Forum, American College of Veterinary Internal Medicine, San Diego, CA, 1998a: 695.

Vaden SL, Hammerberg B, Davenport DJ, et al. Food hypersensitivity reactions in Soft Coated Wheaten Terriers with protein-losing enteropathy or protein-losing nephropathy or both: Gastroscopic food sensitivity testing, dietary provocation, and fecal immunoglobulin E. Journal of Veterinary Internal Medicine 2000; 14: 60-67.

Vaden SL, Sellon RK, Spaulding KA, et al. Early manifestations of protein losing enteropathy and nephropathy in soft coated wheaten terriers (abstract). Canine Practice 1998; 23: 42-43.

Van Kruiningen HJ. Granulomatous colitis of boxer dogs: Comparative aspects. Gastroenterology 1967; 53: 114-122.

Weiss DJ, Gagne JM, Armstrong PJ. Relationship between inflammatory hepatic disease and inflammatory bowel disease, pancreatitis, and nephritis in cats. Journal of the American Veterinary Medical Association 1996; 209: 1114-1116.

Wilcock B. Endoscopic biopsy interpretation in canine or feline enterocolitis. Seminars in Veterinary Medicine and Surgery: Small Animal 1992; 7: 162-171.

Willard MD, Jergens AE, Duncan RB, et al. Interobserver variation among histopathologic examinations of intestinal tissues from dogs and cats. Journal of the American Veterinary Medical Association 2002; 220: 1177-1182.

Williams DA. Gastroenteropathy in Norwegian Lundenhunds in the USA (abstract). In: Proceedings. Fifteenth Annual Veterinary Medical Forum, American College of Veterinary Internal Medicine, Lake Buena Vista, FL, 1997: 661.

Yamasaki K, Suematsu H, Takahashi T. Comparison of gastric and duodenal lesions in dogs and cats with and without lymphocytic-plasmacytic enteritis. Journal of the American Veterinary Medical Association 1996; 209: 95-97.



Box 57-1 Bibliography

Fogle JE, Bissett SA. Mucosal immunity and chronic idiopathic enteropathies in dogs. Compendium on Continuing Education for the Practicing Veterinarian 2007; 29: 290-306.

Guilford WG. Idiopathic inflammatory bowel diseases. In: Guilford WG, Center SA, Strombeck DR, et al, eds. Strombeck’s Small Animal Gastroenterology, 3rd ed. Philadelphia, PA: WB Saunders Co, 1996; 451-486.






Copyright Ⓒ 2019 Mark Morris Institute