Small Animal Clinical Nutrition

The most comprehensive and practical small animal nutrition resource available.

Chapter 7: Antioxidants References


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Chew BP, Park JS, Weng BC, et al. Dietary β-carotene is taken up by blood plasma and leukocytes in dogs. Journal of Nutrition 2000; 130: 1788-1791.

Chew BP, Park JS, Wong TS, et al. Dietary β-carotene stimulates cell-mediated and humoral immune response in dogs. Journal of Nutrition 2000b; 130: 1910-1913.

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Hill AS, Werner JA, Rogers QR, et al. Lipoic acid is 10 times more toxic in cats than reported in humans, dogs or rats. Journal of Animal Physiology and Animal Nutrition (Berlin) 2004; 88: 150-156.

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Hughes G, Murphy MP, Ledgerwood EC. Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate tumour necrosis factor-induced apoptosis: Evidence from mitochondria-targeted antioxidants. Biochemical Journal 2005; 389 (Part 1): 83-89.

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Jewell DE, Toll PW, Wedekind KJ, et al. Effect of dietary antioxidants on concentrations of vitamin E and total alkenals in serum of dogs and cats. Veterinary Therapeutics 2000; 1 (4): 264-272.

Jewell DE, Yu S, Joshi DK. Effects of serum vitamin E levels on skin vitamin E levels in dogs and cats. Veterinary Therapeutics 2002; 3: 235-243.

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Kim HW, Chew BP, Wong TS, et al. Dietary lutein stimulates immune response in the canine. Veterinary Immunology and Immunopathology 2000a; 74: 315-327.

Kim HW, Chew BP, Wong TS, et al. Modulations of humoral and cell-mediated immune responses by dietary lutein in cats. Veterinary Immunology and Immunopathology 2000; 73: 331-341.

Kim YY, Mahan DC. Prolonged feeding of high dietary levels of organic and inorganic selenium to gilts from 25 kg body weight through one parity. Journal of Animal Science 2001; 79: 956-966.

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Magwere T, West M, Murphy MP, et al. The effects of exogenous antioxidants on lifespan and oxidative resistance in Drosophila melanogaster. Mechanisms of Ageing and Development 2006; 170: 356-370.

Marshall RJ, Scott KC, Hill RC, et al. Supplemental vitamin C appears to slow racing greyhounds. Journal of Nutrition 2002; 132 (Suppl. 6): 1616S-1621S.

Massey LK, Liebman M, Kynast-Gales SA. Ascorbate increases human oxaluria and kidney stone risk. Journal of Nutrition 2005; 135: 1673-1677.

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Meydani SN, Hayek M, Wu D, et al. Vitamin E and immune response in aged dogs. In: Reinhart GA, Carey DP, eds. Recent Advances in Canine and Feline Nutrition, vol II. Wilmington, OH: Orange Frazer Press, 1998; 295-303.

Michels AJ, Joisher N, Hagen TM. Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes. Archives of Biochemistry and Biophysiology 2003; 410: 112-120.

Mortola E, Okuda M, Ohno K, et al. Inhibition of apoptosis and virus replication in feline immunodeficiency virus-infected cells by N-acetylcysteine and ascorbic acid. Journal of Veterinary Medical Science 1998; 60: 1187-1193.

Naismith DH. Ascorbic acid requirements of the dog. Proceedings of the Nutrition Society 1958; 17: xlii-xliii.

Neve J. Selenium as a ‘nutraceutical’: How to conciliate physiological and supra-nutritional effects for an essential trace element. Current Opinion in Clinical Nutrition and Metabolic Care 2002; 5: 659-663.

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Phelps DL. Local and systemic reactions to the parenteral administration of vitamin E. Developmental Pharmacology and Therapeutics 1981; 2: 156-171.

Piercy RJ, Hinchcliff KW, DiSilvestro RA, et al. Effect of dietary supplements containing antioxidants on attenuation of muscle damage in exercising sled dogs. American Journal of Veterinary Research 2000; 61: 1438-1445.

Piercy RJ, Hinchcliff KW, Morley PS, et al. Association between vitamin E and enhanced athletic performance in sled dogs. Medicine and Science in Sports and Exercise 2001; 33: 826-833.

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Pillai SR, Traber MG, Steiss JE, et al. Depletion of adipose tissue and peripheral nerve alpha-tocopherol in adult dogs. Lipids 1993a; 28: 1095-1099.

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Yu S, Gross KL. Moderate dietary vitamin C supplement does not affect urinary oxalate concentration in cats. Journal of Animal Physiology and Animal Nutrition (Berlin) 2005; 89: 428-429.

Yu S, Paetau-Robinson I. Dietary supplements of vitamin E and C and beta-carotene reduce oxidative stress in cats with renal insufficiency. Veterinary Research Communications 2006; 30: 403-413.

Zicker SC, Hagen TM, Joisher N, et al. Safety of long-term feeding of dl--lipoic acid and its effect on reduced glutathione: Oxidized glutathione ratios in beagles. Veterinary Therapeutics 2002; 3: 167-176.

Zicker SC. Cognitive and behavioral assessment in dogs and pet food market applications. Progress in Neuropsychopharmacology and Biological Psychiatry 2005; 29; 455-459.



Box 7-1 Bibliography

Beckman KB, Ames BN. The free radical theory of aging matures. Physiological Reviews 1998; 78: 547-581.

Harman D. Aging: A theory based on free radical and radiation chemistry. Journals of Gerontology 1956; 11: 298-300.






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