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Chapter 33: Developmental Orthopedic Disease of Dogs References


AAFCO. (Association of American Feed Control Officials). Official Publication, 2007.

Alexander JE, Moore MP, Wood LLH. Comparative growth studies in Labrador retrievers fed 5 commercial calorie-dense diets. Modern Veterinary Practice 1988; 69: 144-148.

Alexander JE, Wood LLH. Growth studies in Labrador retrievers fed a caloric dense diet: Time-restricted versus free choice feeding. Canine Practice 1987; 14: 41-47.

Allard RL, Douglass GM, Kerr WW. The effect of breed and sex on dog growth. Companion Animal Practice 1988; 2: 15-19.

Arnaud CD, Kolb FO. The calciotropic hormones and metabolic bone disease. In: Greenspan FS, ed. Basic and Clinical Endocrinology. Los Altos, CA: Lange Medical Publications, 1991; 247.

Azria M. The calcitonins. In: Physiology and Pharmacology. Basel, Switzerland: S Karger AG, 1989; 1-152.

Bauer JE, Heinemann KM, Lees GE, et al. Docosahexaenoic acid accumulates in plasma of canine puppies raised on alpha-linolenic acid-rich milk during suckling but not when fed alpha-linolenic acid-rich diets after weaning. Joaurnal of Nutrition 2006; 136 (Suppl. 7): 2087S-2089S.

Baxter JH, Van Wyk JJ. A bone disorder associated with copper deficiency. I. Gross morphological, roentgenological, and chemical observations. Bulletin of the Johns Hopkins Hospital 1953; 93: 1-13.

Belshaw BE, Cooper TB, Becker DV. The iodine requirement and influence of iodine intake on iodine metabolism and thyroid function in the adult beagle. Endocrinology 1975; 96: 1280-1291.

Birch EE, Hoffman DR, Casteneda YS, et al. A randomized controlled trial of long-chain polyunsaturated fatty acid supplementation of formula in term infants after weaning at 6 wk of age. American Journal of Clinical Nutrition 2002; 75: 570-580.

Birge SJ, Avioli LV. Pathophysiology of calcium and phosphate disorders. In: Avioli LV, Krane SM, eds. Metabolic Bone Disease and Clinically Related Disorders. Philadelphia, PA: WB Saunders Co, 1990; 196-221.

Blum JW, Zentek J, Meyer H. Untersuchungen einer unterschiedlichen Energieversorgung auf die Wachstumsintensität und Skelettentwicklung bei wachsenden Doggen. 2. Mitteilung: Einfluß auf den insulinähnlichen Wachstumsfaktor I und die Schilddrüsenhormone. Journal of Veterinary Medicine A 1992; 39: 568-574.

Booles D, Burger IH, Whyte AL, et al. Effect of two levels of zinc intake on growth and trace element status in Labrador puppies. Journal of Nutrition 1991; 121: S79-S80.

Booles D, Poore DW, Legrand-Defretin V, et al. Body composition of male and female Labrador retriever puppies at 20 weeks of age. Journal of Nutrition 1994; 124: S2624-S2625.

Breur GJ, Allen MJ, Carlson SJ, et al. Markers of bone metabolism in dog breeds of different size. Research in Veterinary Science 2004; 76(1): 53-55.

Brewer GJ, Dick RD, Schall W, et al. Use of zinc acetate to treat copper toxicosis in dogs. Journal of the American Veterinary Medical Association 1992; 201: 564-568.

Brinker WO, Piermattei DL, Flo GL, eds. Diagnosis and treatment of orthopedic conditions of the hindlimb. In: Handbook of Small Animal Orthopedics and Fracture Treatment, 2nd ed. Philadelphia, PA: WB Saunders Co, 1990; 341-470.

Brinker WO, Piermattei DL, Flo GL, eds. Osteochondrosis. In: Handbook of Small Animal Orthopedics and Fracture Treatment, 2nd ed. Philadelphia, PA: WB Saunders Co, 1990a; 305-311.

Brinker WO, Piermattei DL, Flo GL. Physical examination for lameness. In: Handbook of Small Animal Orthopedics and Fracture Treatment, 2nd ed. Philadelphia, PA: WB Saunders Co, 1990b; 267-277.

Broadus AE. Mineral balance and homeostasis. In: Favus MJ, ed. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Philadelphia, PA: Lippincott-Raven, 1996; 57-63.

Brown RC, Hoag GN, Smart ME, et al. Alaskan malamute chondrodysplasia. V. Decreased gut zinc absorption. Growth 1978; 42: 1-6.

Carlson CS, Hilley HD, Meuten DJ, et al. Effect of reduced growth rate on the prevalence and severity of osteochondrosis in gilts. American Journal of Veterinary Research 1988; 49: 396-402.

Carlson CS, Meuten DJ, Richardson DC. Ischemic necrosis of cartilage in spontaneous and experimental lesions of osteochondrosis. Journal of Orthopaedic Research 1991; 9: 317-329.

Chakraborty PK, Stewart AP, Seager SW. Relationship of growth and serum growth hormone concentration in the prepubertal bitch. Laboratory Animal Science 1983; 33: 51-55.

Corley EA, Hogan PM. Trends in hip dysplasia control: Analysis of radiographs submitted to the Orthopedic Foundation for Animals 1974 to 1984. Journal of the American Veterinary Medical Association 1985; 187: 805-809.

Daemmrich K, Zentek J, Meyer H. Untersuchungen einer Unterschiedlichen Energieversorgung auf die Wachstumsintensität und Skelettentwicklung bei Wachsenden Doggen. 4. Mitteilung: Pathologisch-Anatomische Untersuchungen 1992.

Daemmrich K. Relationship between nutrition and bone growth in large and giant dogs. Journal of Nutrition 1991; 121: S114-S121.

Danforth E, Burger AG. The impact of nutrition on thyroid hormone physiology and action. Annual Review of Nutrition 1989; 9: 201-227.

Danks DM. Copper deficiency in humans. In: Ciba Foundation Symposium 79, Biological Roles of Copper. Amsterdam: Excerpta Medica, 1980; 209-225.

Daughaday WH, Hall K, Salmon WD, et al. Somatomedin: Proposed designation for sulfation factor. Nature 1972; 235: 107.

Diau G-Y, Loew ER, Wijendram V, et al. Docosahexaenoic and arachidonic acid influence on preterm baboon retinal composition and function. Ophthalmology & Visual Science 2003; 44: 4559-4566.

Dobenencker B, Kienzle E, Matis U. Mal- and overnutrition in puppies with and without clinical disorders of skeletal development (abstract). In: Proceedings. European Society of Veterinary and Comparative Nutrition, Munich, Germany, 1997: 25.

Donoghue S, Szanto J, Kronfeld DS. Hypervitaminosis A in a dog: An example of hospital dietetics. In: Proceedings. Nutrition, Malnutrition, and Dietetics in the Dog and Cat, Hanover, Germany, 1987: 94-96.

Dzanis DA. The AAFCO dog and cat nutrient profiles. In: Bonagura JD, ed. Current Veterinary Therapy XII. Philadelphia, PA: WB Saunders Co, 1995; 1418-1421.

Eigenmann JE, DeBruijne JJ, Froesch ER. Insulin-like-growth factor I and growth hormone in canine starvation. Acta Endocrinologica (Kbh.) 1985; 108: 161-166.

Eigenmann JE. Wachstumshormon und insulinähnlicher Wachstumsfaktor beim Hund: Klinische und experimentelle Untersuchungen. Schweizer Archiv für Tierheilkunde 1986; 128: 57-78.

Eyre DR, Paz MA, Gallop PM. Cross-linking in collagen and elastin. Annual Review of Biochemistry 1984; 53: 717-748.

Eyre DR. Biochemical markers of bone turnover. In: Favus MJ, ed. Primer on Metabolic Bone Diseases and Disorders of Mineral Metabolism, 3rd ed. Philadelphia, PA: Lippincott-Raven, 1996; 114-119.

Feldman EC, Nelson RW, eds. Hypercalcemia and primary hyperparathyroidism. In: Canine and Feline Endocrinology and Reproduction, 2nd ed. Philadelphia, PA: WB Saunders Co, 1996; 455-493.

Froesch ER, Schmid C, Schwander J, et al. Actions of insulin-like growth factors. Annual Review of Physiology 1985; 47: 443-467.

Gessert CF, Phillips PH. Protein in the nutrition of the growing dog. Journal of Nutrition 1956; 58: 415-421.

GfE: Energie- und Nährstoffbedarf. Nr. 5, Hunde. Frankfurt, Germany: DLG Verlag, 1989.

Gilder H, Boskey AL. Dietary lipids and the calcifying tissue. In: Simmons DJ, ed. Nutrition and Bone Development. New York, NY: Oxford University Press, 1990; 244-265.

Glade MJ. The control of cartilage growth in osteochondrosis: A review. Equine Veterinary Science 1984; 6: 1175-1187.

Goedegebuure SA, Hazewinkel HAW. Morphological findings in young dogs chronically fed a diet containing excess calcium. Veterinary Pathology 1986; 23: 594-605.

Goldy GG, Burr JR, Longardner CN, et al. Effects of measured doses of vitamin A fed to healthy beagle dogs for 26 weeks. Veterinary Clinical Nutrition 1996; 3: 42-49.

Hambidge KM, Casey CE, Krebs NF. Zinc. In: Mertz W, ed. Trace Elements in Human and Animal Nutrition. Orlando, FL: Academic Press, 1986; 1-137.

Hansen ES, Fogh K, Hjortdal VE, et al. Synovitis reduced by inhibition of leukotriene B4. Carrageenan induced gonarthritis studied in dogs. Acta Orthopedica Scandinavia 1990; 61: 207-212.

Harris ED, Rayton JK, Balthrop JE, et al. Copper and the synthesis of elastin and collagen. In: Ciba Foundation Symposium 79, Biological Roles of Copper. Amsterdam: Excerpta Medica, 1980; 163-182.

Harris WH, Heaney RP. Skeletal renewal and metabolic disease. New England Journal of Medicine 1969; 280: 193-202.

Hayes KC. On the pathophysiology of vitamin A deficiency. Nutrition Reviews 1971; 29: 3-6.

Hazewinkel HAW, Goedgebuure SA, Poulos PW, et al. Influences of chronic calcium excess on the skeletal development of growing Great Danes. Journal of the American Animal Hospital Association 1985; 21: 377-391.

Hazewinkel HAW, How KL, Bosch R, et al. Ungenugende photosythese von vitamin D bei hunden. In: Meyer H, Kienzle E, eds. Ernahrung, Fehlernahrung und Diaetetik bei Hund und Katze. Hanover, Germany: Dobler Druck, Alfeld, Germany, 1987; 125-129.

Hazewinkel HAW, Vandenbrom WE, Van’t Klooster AT, et al. Calcium metabolism in Great Dane dogs fed diets with various calcium and phosphorous levels. Journal of Nutrition 1991; 121: S99-S106.

Hazewinkel HAW. Nutrition in orthopedics. In: Bojrab MJ, ed. Disease Mechanisms in Small Animal Surgery, 2nd ed. Philadelphia, PA: Lea & Febiger, 1993; 1119-1128.

Hazewinkel HAW. Skeletal disease. In: Wills JM, Simpson KW, eds. The Waltham Book of Clinical Nutrition of the Dog & Cat. Tarrytown, NY: Pergamon, 1994; 395-423.

Hazewinkel HAWH, Schoenmakers I, Pelling D, et al. Biological potency and radioimmunoassay of canine calcitonin. Domestic Animal Endocrinology 1999; 17(4): 333-344.

Hazewinkel HAWH, Theyse LFH, Wolvekamp WTh, et al. The influence of dietary omega-6:omega-3 ratio on lameness in dogs with osteoarthrosis of the elbow joint. In Proceedings: Iams Nutrition Symposium. Recent Advances in Canine and Feline Nutrition, vol. II. Wilmington, OH: Orange Frazer Press, 1998; 325-336.

Hazewinkel HAWH, Tryfonidou MA. Vitamin D3 metabolism in dogs. Molecular and Cellular Endocrinology 2002; 197: 23-33.

Hedhammar A, Wu F, Krook L, et al. Overnutrition and skeletal disease. An experimental study in growing Great Dane dogs. Cornell Veterinarian 1974; 64 (Suppl. 5): 1-160.

Henry GA. Radiographic development of canine hip dysplasia. Veterinary Clinics of North America: Small Animal Practice 1992; 22: 559-578.

Hester PY, Krueger KK, Jackson M. The effect of restrictive and compensatory growth on the incidence of leg abnormalities and performance of commercial male turkeys. Poultry Science 1990; 69: 1731-1742.

High WB, Capen CC, Black HE. Effect of thyroxine on cortical bone remodeling in adult dogs. A histomorphometric study. American Journal of Pathology 1981; 102: 438-446.

Hill MA, Ruth GR, Hilley HD, et al. Dyschondroplasias, including osteochondrosis, of boars between 25 and 169 days of age: Histologic changes. American Journal of Veterinary Research 1984; 45: 903-926.

Hochberg Z, Maor G, Lewinson D, et al. The direct effects of growth hormone on chondrogenesis and osteogenesis. In: Heap RB, Prosser CG, Lamming GE, eds. Biotechnology in Growth Regulation. London, UK: Butterworths, 1989; 123-128.

Hoefling B. Untersuchungen über die Aufzuchtintensität von Junghunden unter besonderer Berücksichtigung der Skelettentwicklung. Thesis. Hanover, Germany, 1989.

Hoffman DR, Birch EE, Castaneda YS, et al. Visual function in breast-fed term infants weaned to formula with or without long-chain polyunsaturates at 4 to 6 months: A randomized clinical trial. Journal of Pediatrics 2003; 142: 669-677.

How KL, Hazewinkel HAW, Mol JA. Dietary vitamin D dependence of cats and dogs due to inadequate cutaneous synthesis of vitamin D. General and Comparative Endocrinology 1994; 96: 12-18.

Hurley LS, Keen CL. Manganese. In: Mertz W, ed. Trace Elements in Human and Animal Nutrition. Orlando, FL: Academic Press, 1986; 185-223.

Isaksson OGP, Lindahl A, Nilsson A, et al. Mechanisms of the stimulatory effect of growth hormone on longitudinal bone growth. Endocrinological Reviews 1987; 8: 426-434.

Jezyk PF, Haskins ME, MacKay-Smith WE, et al. Lethal acrodermatitis in bull terriers. Journal of the American Veterinary Medical Association 1986; 188: 833-839.

Johnson JA, Austin C, Breuer GJ. Incidence of canine appendicular musculoskeletal disorders in 16 veterinary teaching hospitals from 1980-1989. Journal of Veterinary Comparative Orthopedics and Traumatology 1994; 7: 56-69.

Kallfelz FA, Dzanis DA. Overnutrition: An epidemic problem in pet animal practice. Veterinary Clinics of North America: Small Animal Practice 1989; 19: 433-446.

Kasström J. Nutrition, weight gain and development of hip dysplasia. Acta Radiologica Suppl. (Stockholm) 1975; 344: 135-179.

Kealy RD, Olsson SE, Monti KL, et al. Effects of limited food consumption on the incidence of hip dysplasia in growing dogs. Journal of the American Veterinary Medical Association 1992; 210: 857-863.

Keane KW, Nakamura FI, Morris ML. Vitamin A plasma levels of dogs. North American Veterinarian 1947; 28: 587.

Kelley RL, Lepine AJ, Burr JR, et al. Effect of dietary fish oil on puppy trainability. 6th Congress of the International Society for the Study of Fatty Acids and Lipids. 2004: 45338.

Kienzle E, Hall DK. Inappropriate feeding: The importance of a balanced diet. In: Wills JM, Simpson KW, eds. The Waltham Book of Clinical Nutrition of the Dog & Cat. Tarrytown, NY: Pergamon, 1994; 1-14.

Kirchgessner M. Experimentelle Ergebnisse aus der ernährungsphysiologischen und metabolischen Spurenelementforschung. Übersichten zur Tierernährung 1987; 15: 153-192.

Ladlow JF, Hoffmann WE, Breur GJ, et al. Biological variability in serum and urinary indices of bone formation and resorption in dogs. Calcified Tissue International 2002; 70(3): 186-193.

LaFond E, Breur GJ, Austin CC. Breed susceptibility for developmental orthopedic diseases in dogs. Journal of the American Animal Hospital Association 2002; 38(5): 467-477.

Lavelle RB. The effects of overfeeding of a balanced complete commercial diet to a group of growing Great Danes. In: Burger IH, Rivers JW, eds. Nutrition of the Dog and Cat. Cambridge, UK: Cambridge University Press, 1989; 303-315.

Lust G, Geary JC, Sheffy BE. Development of hip dysplasia in dogs. American Journal of Veterinary Research 1973; 34: 87-91.

Lust G, Rendano VT, Summers BA. Canine hip dysplasia: Concepts and diagnosis. Journal of the American Veterinary Medical Association 1985; 187: 638-640.

Martin TJ, Moseley JM. Calcitonin. In: Avioli LV, Krane SM, eds. Metabolic Bone Disease and Clinically Related Disorders. Philadelphia, PA: WB Saunders Co, 1990; 131-154.

Meyer H, Zentek J. Energy requirements of growing Great Danes. Journal of Nutrition 1991; 121: S35-S36.

Meyer H, Zentek J. Über den Einfluß einer unterschiedlichen Energieversorgung wachsender Doggen auf Körpermasse und Skelettentwicklung. Journal of Veterinary Medicine A 1992; 39: 130-141.

Meyer H, Zentek J. Untersuchungen zum Wachstum verschiedener Hunderassen in Abhängigkeit von der Fütterung. Proc. 35. Jahrestagung, Deutsche Veterinärmedizinische Gesellschaft, Fachgruppe Kleintierkrankheiten, Gießen (FRG); 1989: 39-50.

Meyer H. In: Ernährung des Hundes, 2nd ed. Stuttgart, Germany: Auflage. Eugen Ulmer, 1990.

Nakano T, Aherne FX. The pathogenesis of osteochondrosisA hypothesis. Medical Hypotheses 1994; 43: 1-5.

Nap RC, Hazewinkel HAW, Voorhout G, et al. Growth and skeletal development in miniature poodles fed different levels of calcium. In: Nap RC, ed. Nutritional Influences on Growth and Skeletal Development in the Dog. Thesis. Proefschrift, Utrecht, 1993a; 75-93.

Nap RC, Hazewinkel HAW, Voorhout G, et al. Growth and skeletal development in Great Dane pups fed different levels of protein intake. Journal of Nutrition 1991; 121: S107-S113.

Nap RC, Hazewinkel HAW, Voorhout G, et al. The influence of the dietary protein content on growth in giant breed dogs. Journal of Veterinary Comparative Orthopedics and Traumatology 1993b; 6: 1-8.

Nap RC, Hazewinkel HAW. Growth and skeletal development in the dog in relation to nutrition: A review. Veterinary Quarterly 1994; 16: 50-59.

Nap RC, Mol JA, Hazewinkel HAW. Age-related plasma concentrations of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) in Great Dane pups fed different dietary levels of protein. Domestic Animal Endocrinology 1993; 10: 237-247.

Nap RC. Nutritional influences on growth and skeletal development in the dog. Thesis. Proefschrift, Rijksuniversiteit Utrecht, 1993.

NRC. (National Research Council). Nutrient Requirements of Dogs and Cats. Washington, DC: National Academies of Sciences, 2006.

Nunez EA, Hedhammar A, Wu FM, et al. Ultrastructure of the thyroid C cells and the parathyroid cells in growing dogs on a high calcium diet. Laboratory Investigation 1974; 31: 96-108.

Oveido-Rondon EO, Ferket PR, Havenstein GB. Nutritional factors that affect leg problems in broilers and turkeys. Avian and Poultry Biology Reviews 2006; 17: 89-103.

Pawlosky RJ, Denkins Y, Ward G, et al. Retinal and brain accretion of long-chain polyunsaturated fatty acids in developing felines: The effects of corn oil-based maternal diets. American Journal of Clinical Nutrition 1997; 65: 465-472.

Prout RES, Tring FC. Periodontal changes in the rat induced by fat free diet. Journal of Periodontal Research 1971; 6: 182-187.

Rainbird A, Kienzle E. Untersuchungen zum Energiebedarf des Hundes in Abhängigkeit von Rassezugehörigkeit und Alter. Kleintierpraxis 1990; 35: 149-158.

Read RA, Kent GN, Price RI. Inhibition of osteoblastic function in the osteoporosis of copper deficiency in dogs. Journal of Veterinary Comparative Orthopedics and Traumatology 1989; 1: 25-40.

Richardson DC, Toll PW. Relationship of nutrition to developmental skeletal disease in young dogs. Veterinary Clinical Nutrition 1997; 4: 6-13.

Richardson DC, Zentek J, Hazewinkel HAW, et al. Developmental Orthopedic Disease of Dogs. In. Hand MS, Thatcher CD, Remillard RL, et al, eds. Small Animal Clinical Nutrition, 4th ed. Topeka, KS: Mark Morris Institute 2000; 505-528.

Richardson DC. Developmental orthopedics: Nutritional influences in the dog. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine, 4th ed. Philadelphia, PA: WB Saunders Co, 1995; 252-257.

Richardson DC. The role of nutrition in canine hip dysplasia. Veterinary Clinics of North America: Small Animal Practice 1992; 22: 529-540.

Riser WH, Cohen D, Linquist S, et al. Influence of early rapid growth and weight gain on hip dysplasia in the German Shepherd dog. Journal of the American Veterinary Medical Association 1964; 145: 661-668.

Robey PG, Termine JD. Biochemical markers of metabolic bone disease. In: Avioli LV, Krane SM, eds. Metabolic Bone Disease and Clinically Related Disorders, 2nd ed. Philadelphia, PA: WB Saunders Co, 1990; 244-263.

Romsos DR, Belo PS, Bennink MR, et al. Effects of dietary carbohydrate, fat and protein on growth, body composition and blood metabolite levels in the dog. Journal of Nutrition 1976; 106: 1452-1464.

Saunders HM, Jezyk PF. The radiographic appearance of canine congenital hypothyroidism: Skeletal changes with delayed treatment. Veterinary Radiology 1991; 32: 171-177.

Schoenmakers I, Hazewinkel HAW, Voorhut G, et al. Calcium and phosphorous absorption and retention in Great Danes raised on foods with different calcium and phosphorous contents (abstract). European Society of Veterinary Comparative Nutrition 1997; 24.

Schoenmakers I, Hazewinkel HAWH, Voorhout G, et al. Effects of diets with different calcium and phosphorus contents on skeletal development and blood chemistry of growing Great Danes. Veterinary Record 2000; 147: 652-660.

Sheng HP, Huggins RA. Growth of the beagle: Changes in chemical composition. Growth 1971; 35: 369-376.

Siegel RC. Lysyl oxidase. International Review of Connective Tissue Research 1979; 8: 73-118.

Slater MR, Scarlett JM, Donoghue S, et al. Diet and exercise as potential risk factors for osteochondritis dissecans in dogs. American Journal of Veterinary Research 1992; 53: 2119-2124.

Slater MR, Scarlett JM, Kaderly RE, et al. Breed, gender, and age risk factors for canine osteochondritis dissecans. Journal of Veterinary Comparative Orthopedics and Traumatology 1991; 4: 100-106.

Smart ME, Fletch S. A hereditary growth defect in purebred Alaskan malamutes. Canadian Veterinary Journal 1971; 12: 31-32.

Takeuchi H, Matsuo T, Tokuyama K, et al. Serum triiodothyronine concentration and Na+ K+ -ATPase activity in liver and skeletal muscle are influenced by dietary fat type in rats. Journal of Nutrition 1995; 125: 2364-2369.

Tanaka Y, DeLuca HF. The control of 25-hydroxyvitamin D metabolism by inorganic phosphorous. Archives of Biochemistry and Biophysiology 1977; 154: 566-574.

Teare JA, Krook L, Kallfelz FA, et al. Ascorbic acid deficiency and hypertrophic osteodystrophy in the dog: A rebuttal. Cornell Veterinarian 1979; 69: 384-401.

Tenenhouse HS. The vitamin D endocrine system. In: Simmons DJ, ed. Nutrition and Bone Development. New York, NY: Oxford University Press, 1990; 164-201.

Toll PW, Richardson DC, Jewell DE, et al. The effect of feeding method on growth and body composition in young puppies (abstract). In: Proceedings. Waltham Symposium on the Nutrition of Companion Animals, Adelaide, Australia, 1993: 33.

Tryfonidou MA, Holl MS, Vastenburg M, et al. Hormonal regulation of calcium homeostasis in two breeds of dogs during growth at different rates. Journal of Animal Science 2003b; 81: 1568-1580.

Tryfonidou MA, Oosterlaken-Dijksterhuis MA, Mol JA, et al. 24 hydroxylase: Potential key regulator in hypervitaminosis D3 in growing dogs. American Journal of Physiology 2003a; 284: E505-E513.

Tryfonidou MA, Stevenhagen JJ, Buurman CJ, et al. Dietary 135-fold cholecalciferol supplementation severely disturbs the endochondral ossification in growing dogs. Domestic Animal Endocrinology 2003; 24(4): 265-285.

Tryfonidou MA, van den Broek JJ, van den Brom WE, et al. Intestinal calcium absorption in growing dogs is influenced by calcium intake and age, but not by growth rate. Journal of Nutrition 2002; 132: 3363-3368.

Voorhout A, Hazewinkel HAW. A radiographic study on the development of the antebrachium in Great Dane pups on different calcium intakes. Veterinary Radiology 1987; 28: 152-157

Watkins BA, Shen C-L, McMurty JP, et al. Dietary lipids modulate bone prostaglandin E2 production, insulin-like growth factor-I concentration and formation rate in chicks. Journal of Nutrition 1997; 127: 1084-1091.

Weisbrode SE, Capen CC. The ultrastructural effects of parathyroid hormone, calcitonin, and vitamin D on bone. In: Bonucci E, Motta PM, eds. Ultrastructure of Skeletal Tissues. Bone and Cartilage in Health and Disease. Dordrecht, The Netherlands: Academic Publishing, 1990; 253-269.

Wiersig DO, Swenson MJ. Teratogenicity of vitamin A in the canine. Federal Proceedings 1967; 26: 486.

Zentek J, Daemmrich K, Meyer H. Untersuchungen zum Cu-Mangel beim Wachsenden Hund. Journal of Veterinary Medicine A 1991; 38: 561-570.

Zentek J, Meyer H, Daemmrich K. Untersuchungen einer Unterschiedlichen Energieversorgung auf die Wachstumsintensität und Skelettentwicklung bei Wachsenden Doggen. 3. Mitteilung: Klinisches Bild und chemische Skelettuntersuchungen. Journal of Veterinary Medicine A 1995; 42: 69-80.

Zentek J, Meyer H. Energieaufnahme adulter Deutscher Doggen. Berliner und Münchener Tierärztliche Wochenschrift 1992; 105: 325-327.

Zentek J. Beobachtungen zur scheinbaren Verdaulichkeit von Kupfer, Zink, Eisen und Mangan beim Hund. Deutsche Tierärztliche Wochenschrift 1995; 108: 310-315.



Box 33-1 Bibliography


Schneider S, Breit SM, Grampp S, et al. Comparative assessment of bone mineral measurements obtained by use of dual-energy x-ray absorptiometry, peripheral quantitative computed tomography, and chemical-physical analyses in femurs of juvenile and adult dogs. American Journal of Veterinary Research 2004; 65(7): 891-900.

Toll PW, Anderson DE, Berryhill SA, et al. The effect of storage of excised bone on measurement of bone mineral using dual energy x-ray absorptiometry (DEXA). Journal of Bone Mineral Research 1994; 9 (Suppl.): S185.

Toll PW, Berryhill SA, Jewell DE. Usefulness of dual energy x-ray absorptiometry (DEXA) for body composition assessment in nutritional studies of dogs. Waltham Symposium on the Nutrition of Companion Animals, Adelaide, Australia, 1993.

Wedekind KW, Toll PW, Richardson DC, et al. Validation of dual energy x-ray absorptiometry as a quantitative measure of body composition in small subjects (abstract). Journal of Bone Mineral Research 1992; 7 (Suppl. 1): S256.



Box 33-2 Bibliography

Glimcher MJ. The nature of the mineral composition of bone and the mechanism of calcification. In: Avioli LV, Krane SM, eds. Metabolic Bone Disease and Clinically Related Disorders, 2nd ed. Philadelphia, PA: WB Saunders Co, 1990; 42-68.



Box 33-3 Bibliography

Abu Damir HD, Scott N, Loveridge W, et al. The effect of feeding diets containing either NaHCO3 or NH4Cl on indices of bone formation and resorption and on mineral balance in the lamb. Experimental Physiology 1991; 76: 725-732.

Kealy RD, Lawler DF, Monti KL, et al. Effects of dietary electrolyte balance on subluxation of the femoral head in growing dogs. American Journal of Veterinary Research 1993; 54: 555-562.

Mongin P. Recent advances in dietary anion-cation balance: Applications in poultry. Proceedings of the Nutrition Society 1981; 40: 285-294.

Patience JF. The physiological basis of electrolytes in animal nutrition. In: Haresign W, Cole DJA, eds. Recent Advances in Animal Nutrition. London, UK: Butterworths, 1989; 223-228.

Poulos PW, Reiland S, Elwinger K, et al. Skeletal lesions in the broiler, with special reference to dyschondroplasia (osteochondrosis). Acta Radiologica Suppl. (Stockholm) 1978; 358: 197-227.

Van der Wal PG, Hemminga H, Goedegebuure SA, et al. The effect of replacement of 0.30% sodium chloride by 0.43% sodium bicarbonate in rations of fattening pigs on leg weakness, osteochondrosis and growth. Veterinary Quarterly 1994; 8: 136-144.



Box 33-5 Bibliography

Kallfelz FA, Dzanis DA. Overnutrition: An epidemic problem in pet animal practice. Veterinary Clinics of North America: Small Animal Practice 1989; 19: 433-446.






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